HOW OUR PROGRAMME WORKS

Your weight-management journey, explained

Wegovy & Mounjaro – Clinician-Led Weightloss Clinic

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ELIGIBILITY

Is our programme right for you?

Eligibility is based mainly on your BMI. Final suitability is always confirmed by our prescriber after reviewing your full form.

BMI 30+

Eligible on BMI alone - no additional weight-related condition needed.

BMI 27-29.9

Eligible only if you also have a recognised weight-related health condition.

Below BMI 27

Not eligible under standard licensing, regardless of other conditions.

These treatments are not suitable for anyone who is pregnant, breastfeeding or trying to conceive. Not sure of your BMI? Use the free NHS BMI calculator, or leave it blank on the form and we’ll work it out from your height and weight.

Wegovy

Clinically proven fat reduction

Treatment specifically designed for weight management. It supports significant fat loss when combined with healthy lifestyle changes.

Yes and no. Whilst they are both the medication known as semaglutide, Ozempic is licensed for the treatment of diabetes – using it for weight loss alone is not licensed in the UK. The dosage regime for Ozempic vs Wegovy is different too. But it hasn’t stopped many clinics giving it out, without proper assessment or any thought for the many diabetics who rely on it for treatment and are having trouble accessing it.

The precise mechanism of action is not completely clear, but it appears to act by reducing appetite and clearly has some effect on stabilising blood sugar too.

Wegovy comes in the form of an injection, given by a small pen that provides a carefully measured dose. The injection needle is so tiny you can barely feel it and can be done, yourself, at home after you have been instructed by a healthcare professional on how and where to inject. The injection is performed just once a week and the dose is gradually increased over several weeks.

In some people it can cause nausea which can lead to some people giving up altogether. Abdominal pain, constipation or diarrhoea can occur too. These side-effects are usually mild and can be reduced by building up the dose slowly to allow the body time to adjust.

Mounjaro

Advanced dual-action treatment

Targets both appetite and blood sugar regulation, offering highly effective results for weight loss.

Mounjaro is administered via subcutaneous injection. The typical starting dose is 2.5 mg once weekly, which may be increased based on individual patient needs and tolerability. The maximum recommended dose is 15 mg per week. Patients should follow their healthcare provider’s instructions carefully regarding dosage adjustments.

While Mounjaro has shown promising results, it is essential to be aware of potential side effects, which may include:

– Nausea
– Vomiting
– Diarrhea
– Constipation
– Abdominal pain

Most side effects are mild to moderate and tend to decrease over time. However, serious side effects, such as pancreatitis and kidney impairment, have been reported. Patients should be monitored for these conditions, and Mounjaro should not be used in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.

This varies from person to person. Some patients notice changes within the first few weeks, but meaningful weight loss typically builds over several months. We track your progress at every follow-up.

Mounjaro (tirzepatide) is a groundbreaking medication developed by Eli Lilly and Company, primarily designed for the treatment of type 2 diabetes. Approved by the FDA in May 2022, Mounjaro represents a new class of drugs known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists. This innovative approach not only helps in managing blood sugar levels but also offers potential benefits for weight management.

Mechanism of Action

Mounjaro works by mimicking the effects of two hormones that play a critical role in glucose metabolism:

1. GIP (Glucose-Dependent Insulinotropic Polypeptide): Stimulates insulin secretion in response to food intake while also inhibiting glucagon secretion, helping to lower blood glucose levels.

2. GLP-1 (Glucagon-Like Peptide-1): Enhances insulin secretion, slows gastric emptying, and promotes satiety, contributing to weight loss.

By activating both pathways, Mounjaro offers a multifaceted approach to diabetes management, improving glycemic control and aiding in weight reduction.

 

Dosage and Administration

Mounjaro is administered via subcutaneous injection. The typical starting dose is 2.5 mg once weekly, which may be increased based on individual patient needs and tolerability. The maximum recommended dose is 15 mg per week. Patients should follow their healthcare provider’s instructions carefully regarding dosage adjustments.

Efficacy

Clinical trials have demonstrated that Mounjaro significantly lowers HbA1c levels, a key marker of long-term blood glucose control. In addition to improving glycemic control, participants in clinical studies also experienced significant weight loss compared to those on placebo. These results highlight Mounjaro’s dual benefits for individuals managing both diabetes and weight.

Safety and Side Effects

While Mounjaro has shown promising results, it is essential to be aware of potential side effects, which may include:

– Nausea
– Vomiting
– Diarrhea
– Constipation
– Abdominal pain

Most side effects are mild to moderate and tend to decrease over time. However, serious side effects, such as pancreatitis and kidney impairment, have been reported. Patients should be monitored for these conditions, and Mounjaro should not be used in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.

 

Contraindications and Precautions

Mounjaro is contraindicated in:

– Patients with a history of serious hypersensitivity reactions to tirzepatide or any of its components.
– Those with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.

Patients should consult with their healthcare provider to discuss their medical history and any potential interactions with other medications.

Lifestyle Considerations

For optimal results, Mounjaro should be used in conjunction with a balanced diet and regular physical activity. Patients are encouraged to engage in lifestyle modifications that support their health goals, such as:

– Adopting a nutrient-dense diet rich in whole foods
– Incorporating regular exercise
– Monitoring blood glucose levels as advised by healthcare providers

Conclusion

Mounjaro represents a significant advancement in the management of type 2 diabetes and obesity. With its unique dual-action mechanism, it provides patients with an effective option to improve glycemic control and support weight loss efforts. As with any medication, it is crucial for patients to work closely with their healthcare providers to establish a comprehensive treatment plan tailored to their individual needs.

Wegovy Pill (Oral Semaglutide)

The Wegovy pill contains semaglutide, the same active ingredient used in the Wegovy injection, but delivered as a once-daily tablet rather than a weekly injection. It is designed for people who would prefer to avoid needles while still accessing the same underlying treatment.

Semaglutide belongs to a class of medicines called GLP-1 receptor agonists. It works by mimicking a naturally occurring gut hormone that helps regulate appetite. This helps people feel fuller for longer, reduces hunger, and supports eating less overall. The tablet has a specialised coating that helps protect the medicine as it passes through the stomach, supporting absorption. It is intended to be used alongside a reduced-calorie diet and increased physical activity.

The tablet is taken once daily, first thing in the morning, on an empty stomach, with no more than a small amount of plain water. Patients should then wait at least 30 minutes before eating, drinking anything other than water, or taking any other oral medicines, to allow proper absorption.

Dosing typically follows a gradual escalation schedule, for example:

• Initial dose: a low starting dose taken daily for the first month

• Dose increases: the dose is increased at intervals over the following months, as guided by the prescriber

• Maintenance dose: patients reach an ongoing daily maintenance dose once titration is complete

The exact schedule and final maintenance dose should always be confirmed and adjusted by the prescribing clinician based on individual response and tolerability.

• A needle-free alternative to the Wegovy injection, using the same active ingredient

• Supports appetite reduction and feeling fuller for longer

• Used alongside diet and exercise as part of a wider weight management plan

• Clinical trial data has shown meaningful average weight loss over sustained use (around 64 weeks) when combined with lifestyle changes

The most commonly reported side effects are gastrointestinal, particularly when starting treatment or increasing the dose. These include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Indigestion (dyspepsia)

• Stomach pain or discomfort

• Headache

• Fatigue

Side effects are generally most noticeable during dose increases and tend to settle over time. Patients should be advised to speak to their prescriber about any side effects, especially if they are severe or persistent.

SAFETY & TRUST

Care you can rely on

Regulated pharmacy

Dispensed by a GPhC-regulated UK pharmacy.

Registered prescribers

Prescribed by qualified GMC or GPhC professionals.

Genuine medication

Sourced from regulated UK wholesalers and suppliers.

Your data protected

Handled securely and protected in line with GDPR.

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QUESTIONS & ANSWERS

Frequently asked questions

Everyone is different, so we avoid promising specific timescales. Steady, lasting results come from staying consistent alongside lifestyle changes and the clinical support we provide. Your prescriber will talk through what’s realistic for you.

These treatments can be available on the NHS, but usually with stricter BMI and health thresholds, a referral pathway and waiting lists. Our private route is designed to be quicker and more convenient, with support built in.

Possibly, and that’s exactly what the medical history section of the form is for. It lets our prescriber assess your safety individually and advise on any risks before you start.

Not necessarily. The current medications section of the form lets our prescriber check for any interactions (for example with insulin or blood-thinning medication) before approving treatment.

Common reasons include a BMI below the eligible range, being pregnant or breastfeeding, or a personal or family medical history that means treatment needs your GP’s input first. Your prescriber will always explain why.

Your treatment is overseen by registered prescribers (doctors registered with the GMC or prescribing pharmacists registered with the GPhC), working within current MHRA and NICE guidance.

Free consultation – this month only

Check your eligibility

Complete the short form below and our team will review it and be in touch to arrange your free Zoom consultation. This is not a purchase – no payment is taken here, and any treatment decision is made by our prescriber.

Please answer honestly – it helps us keep your treatment safe. Takes about 5 minutes.

Ascot Weight Loss & Wellness - Assessment

Tablet or injection - the choice is yours

Both options are clinically proven and MHRA-approved. Your clinician will help you decide which fits your lifestyle best.

Two ways to reach your goal

Tablet

Taken once a day, no needles involved, no fridge storage needed

Injection

Taken once a week, tends to deliver the strongest results, needs to be kept refrigerated

Our patients lose between 2 and 4 lbs a month

Real results from real patients on our GLP-1 treatment programme.

Have you ever been diagnosed with any of the following?

Where relevant, our clinical team may ask you for supporting evidence of a diagnosis during your consultation.

Got a question about your medication, noticed a side effect, or just want some reassurance? Our team is only ever a message away.

Neil Gathani Superintendent Pharmacist, Ascot Weight Loss & Wellness
 
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